Title :
The bio-labeled nanodiamond arrays on silicon templates for bio-sensing applications
Author :
Liu, Y.L. ; Sun, K.W.
Author_Institution :
Dept. of Appl. Chem., Nat. Chiao Tung Univ., Hsinchu, Taiwan
Abstract :
The surface modified (carboxylation or oxidation) nanodiamonds provide the chemical or physical conjugation with the bio-molecules to form the bio-functionalized nanodiamonds. The protein lysozyme absorbed on nanodiamonds can interact with E. coli bacterial cells. The lysozyme-nanodiamonds complexes were demonstrated to retain their antibacterial activity which allows constructing the indicator system (bio-sensors).
Keywords :
antibacterial activity; biochemistry; biosensors; diamond; enzymes; molecular biophysics; nanobiotechnology; oxidation; C; E.coli bacterial cells; Si; absorption; antibacterial activity; bio-labeled nanodiamond arrays; biomolecules; biosensors; carboxylation; chemical conjugation; lysozyme-nanodiamonds complexes; oxidation; physical conjugation; protein lysozyme; silicon templates; surface modified nanodiamonds; Anti-bacterial; Biomedical optical imaging; Bonding; Microorganisms; Nanobioscience; Optical arrays; Proteins; Scanning electron microscopy; Silicon; Throughput;
Conference_Titel :
Nanoelectronics Conference (INEC), 2010 3rd International
Conference_Location :
Hong Kong
Print_ISBN :
978-1-4244-3543-2
Electronic_ISBN :
978-1-4244-3544-9
DOI :
10.1109/INEC.2010.5424828
