DocumentCode
1667367
Title
An ultrasensitive optofluidic nucleic acid biosensor
Author
Measor, Philip ; Zhao, Yue ; Hawkins, Aaron R. ; Schmidt, Holger
Author_Institution
Baskin Sch. of Eng., Univ. of California, Santa Cruz, CA, USA
fYear
2012
Firstpage
1
Lastpage
2
Abstract
Amplification-free nucleic acid testing using molecular beacon detection on an optofluidic chip is reported. A limit of detection at the single molecule detection level (10pM) and excellent specificity (single nucleotide mismatches) is observed.
Keywords
bioMEMS; biosensors; chemical sensors; integrated optics; macromolecules; micro-optomechanical devices; microfluidics; microsensors; molecular biophysics; optical sensors; patient diagnosis; amplification-free nucleic acid testing; microsensors; molecular beacon detection; optofluidic chip; single molecule detection level; single nucleotide mismatches; ultrasensitive optofluidic nucleic acid biosensor; Biosensors; Diseases; Educational institutions; Fluorescence; Optical device fabrication; Optical sensors;
fLanguage
English
Publisher
ieee
Conference_Titel
Lasers and Electro-Optics (CLEO), 2012 Conference on
Conference_Location
San Jose, CA
Print_ISBN
978-1-4673-1839-6
Type
conf
Filename
6326173
Link To Document