Title :
Patient-Specific Hemodynamic Analysis for Cerebral Aneurysm
Author :
Wang, Shengzhang ; Chen, Jialiang ; Yang, Xinjian ; Zhang, Xiaolong
Author_Institution :
Dept. of Mech. & Eng. Sci., Fudan Univ., Shanghai
Abstract :
Cerebrovascular diseases are one of the three major mortalities in China, such as the rupture of cerebral aneurysm. The growth mechanism of the cerebral aneurysm has not been clearly understood. In this research, we are introducing a numerical simulation tool, computational fluid dynamics (CFD) technique, to simulate and predict the hemodynamics of blood passing through the cerebral aneurysms. Endovascular coils occlusion is a main surgery treatment to the cerebral aneurysms and the hemodynamic factors should change a lot after the coiling treatment, but there is no quantitative way to evaluate the effect of the coiling treatment. Such image- based CFD analysis may be used to provide key hemodynamic information for prospective studies of aneurysm regrowth of an individual aneurysm or evaluating the effect of the endovascular coils occlusion. Appropriate computational techniques show great promise in simulating the hemodynamic behavior before and after coil occlusion and may be a potentially valuable tool in studying the regrowth reasons of the leaving residual neck remnant. In this article, hemodynamic analysis of the cerebral aneurysm before and after coiling treatment were done. The results revealed that the speed flow changed a little bit in the artery but the wall shear stress reduced more than 50% percent of the aneurysm at the proximal and distal ends of the neck.
Keywords :
biomedical imaging; blood vessels; computational fluid dynamics; diseases; flow simulation; haemodynamics; medical computing; neurophysiology; numerical analysis; surgery; cerebral aneurysm growth mechanism; cerebrovascular diseases; computational fluid dynamics; computational techniques; endovascular coil occlusion; hemodynamic factors; image-based CFD analysis; numerical simulation tool; patient-specific hemodynamic analysis; residual neck remnant; surgery treatment; wall shear stress; Aneurysm; Blood; Coils; Computational fluid dynamics; Computational modeling; Diseases; Hemodynamics; Neck; Numerical simulation; Predictive models;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
DOI :
10.1109/ICBBE.2008.765