Ultrasonic characterization of ultrasound contrast agents

Author

Schmitt, R.M. ; Schmidt, H.J. ; Irion, A.

Author_Institution

Dept. of Biomed. Eng., Fraunhofer-Inst. for NDT, Konstanz, West Germany

fYear

1989

Firstpage

429

Abstract

Materials and models for an experimental system designed and built for the parallel determination of various acoustic properties in microbubble-based contrast agents are discussed. The intersection of three acoustic beams determines the volume of interaction between the microbubbles and the acoustic waves. Preliminary results on ultrasonic propagation parameter measurements indicate that highly concentrated contrast agents are greatly affecting sound attenuation, velocity, and backscattering. At shelf concentrations self-absorption due to multiple scattering becomes dominant and imaging is disturbed by artifacts

Keywords

acoustic imaging; biomedical ultrasonics; patient diagnosis; acoustic backscattering; acoustic properties; acoustic waves; diagnostic ultrasound; image artifacts; microbubble-based contrast agents; multiple scattering; self-absorption; sound attenuation; sound velocity; ultrasonic characterisation; ultrasonic propagation parameter measurements; ultrasound contrast agents; Acoustic beams; Acoustic materials; Acoustic measurements; Acoustic propagation; Acoustic waves; Attenuation measurement; Backscatter; Ultrasonic imaging; Ultrasonic variables measurement; Velocity measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in

Conference_Location

Seattle, WA

Type

conf

DOI

10.1109/IEMBS.1989.95803

Filename

95803