Localization and Atlas-Based Segmentation of the Heart from Cardiac MR Images: Validation with a Large Clinical Trial

Author

Lin, Xiang ; Young, Alistair ; Cowan, Brett

Author_Institution

Auckland Bioeng. Inst., Univ. of Auckland, Auckland

fYear

2008

Firstpage

2319

Lastpage

2322

Abstract

This paper presents an automatic method to find and segment the boarders of the left and right ventricles (LV and RV) from the middle short axis (SA) slice of a functional cardiac MRI study. The segmentation is implemented using a new atlas-based registration framework which is able to integrate boundary, intensity and anatomical information. The method is shown to be accurate, robust and reliable in a clinical trial of 330 patients with a range of cardiac and vascular disease. The method failed in only two cases, and showed high agreement with expert observers in the remaining 328.

Keywords

biomagnetism; biomedical MRI; cardiovascular system; diseases; image segmentation; atlas-based segmentation; cardiac disease; functional cardiac MR images; heart; left ventricle; middle short axis slice; right ventricle; vascular disease; Blood; Clinical trials; Heart; Image segmentation; Interpolation; Labeling; Magnetic resonance imaging; Muscles; Myocardium; Robustness;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on

Conference_Location

Shanghai

Print_ISBN

978-1-4244-1747-6

Electronic_ISBN

978-1-4244-1748-3

Type

conf

DOI

10.1109/ICBBE.2008.912

Filename

4535792