Analysis of heart rate and blood pressure variability during nasal continuous positive airway pressure therapy in patients with obstructive sleep apnea

Author

Glos, M. ; Romberg, D. ; Fietze, I. ; Röttig, J. ; Knobe, M. ; Witt, Ch.

Author_Institution

Univ. Hosp. Charite, Berlin, Germany

fYear

1999

fDate

6/21/1905 12:00:00 AM

Firstpage

603

Lastpage

605

Abstract

We investigated the effect of a nasal continuous positive airway pressure (nCPAP) therapy on low frequency (LF) and high frequency (HF) parameters of the heart rate variability (HRV) and the systolic blood pressure variability (SBPV). All recordings were done one day before and two days after initiation of nCPAP during daytime and applied nasal ventilation. Fourier analysis was calculated with a developed software. The power spectral density (PSD) of beat to beat time series was given according to the method of Welch (1967). LF and HF parameters of HRV and SBPV were calculated by integration of spectral components. Within two nights of nCPAP therapy the HRV parameters changed significantly, but no changes were found on the SBPV parameters. The analysis of HRV and SBPV in the frequency domain appears to be a sensitive marker of the therapeutic effects of nCPAP on the autonomic tone

Keywords

Fourier analysis; biocontrol; cardiovascular system; electrocardiography; haemodynamics; medical signal processing; neurophysiology; patient treatment; pneumodynamics; sleep; spectral analysis; time series; Fourier analysis; applied nasal ventilation; autonomic nervous system; autonomic tone; beat to beat time series; blood pressure variability; daytime; frequency domain; heart rate variability; high frequency parameters; low frequency parameters; nasal continuous positive airway pressure therapy; obstructive sleep apnea; patients; power spectral density; spectral components; systolic blood pressure variability; therapeutic effects; Blood pressure; Blood pressure variability; Frequency; Hafnium; Heart rate; Heart rate variability; Medical treatment; Sleep apnea; USA Councils; Ventilation;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology, 1999

Conference_Location

Hannover

ISSN

0276-6547

Print_ISBN

0-7803-5614-4

Type

conf

DOI

10.1109/CIC.1999.826043

Filename

826043