Title :
Shape control of side effect machines for DNA classification
Author :
McEachern, Andrew ; Ashlock, Daniel
Author_Institution :
Dept. of Math. & Stat., Univ. of Guelph, Guelph, ON, Canada
Abstract :
Side effect machines are augmented finite state machines with counters on each state. They are used to convert DNA or other string data into numerical features. In this study we examine the effect of imposing shapes on side effect machines. When a standard finite state device is programmed with an evolutionary algorithm there is no restriction placed on the transition function. A shape for a population of evolving finite state machines is a restriction on the possible transitions. We demonstrate that choosing a shape with expert knowledge yields improved performance on a supervised classification task. The shapes used are designed, induced from evolved side effect machines, and designed based on features of evolved side effect machines. The best performance was exhibited by a shape induced from an evolved side effect machine.
Keywords :
DNA; biology computing; evolutionary computation; feature extraction; finite state machines; learning (artificial intelligence); molecular biophysics; numerical analysis; pattern classification; shape control; DNA classification; augmented finite state machines; evolutionary algorithm; expert knowledge; numerical features; shape control; side effect machines; standard finite state device; string data; supervised classification task; transition function; Charge carrier processes; DNA; Shape; Sociology; Standards; Statistics; Training;
Conference_Titel :
Computational Intelligence in Bioinformatics and Computational Biology, 2014 IEEE Conference on
Conference_Location :
Honolulu, HI
DOI :
10.1109/CIBCB.2014.6845519