Title :
A MRI compatible optical system and its respiration adaptive estimation method for hemoglobin concentration in mice brain
Author :
Liang Deng ; Wen-hui Yang ; Yi-kai Shi
Author_Institution :
Inst. of Electr. Eng., Beijing, China
Abstract :
We propose a design of a integrated system of optic fibers and a superconducting surface coil. A MRI compatible support fixed the optic fiber and the coil, and the optic fibers installed through the air gap. In order to compensate the periodic errors of the hemoglobin concentration estimation produced by the respiration and heart rate of subjects, we propose the generalized least square method to acquire the adaptive estimation, which considers the noise variance of the temporal optical measurements as a time-varying model. The vivo experiments that the optical-sensing simultaneously working with MRI scans are conducted to characterize the performance of this approach.
Keywords :
adaptive estimation; biomedical MRI; biomedical optical imaging; brain; cardiology; fibre optic sensors; image fusion; least squares approximations; medical image processing; molecular biophysics; pneumodynamics; proteins; superconducting coils; MRI compatible optical system; air gap; generalized least square method; heart rate; hemoglobin concentration estimation; integrated system; mice brain; noise variance; optic fibers; optical sensing; periodic errors; respiration adaptive estimation method; superconducting surface coil; temporal optical measurements; time-varying model; Educational institutions; Image segmentation; Magnetic resonance imaging; Optical fiber theory; Signal resolution; Spatial resolution; Adaptive estimation; Optical-MRI fusion; respiration and cardiac rate;
Conference_Titel :
Electronics, Computer and Applications, 2014 IEEE Workshop on
Conference_Location :
Ottawa, ON
DOI :
10.1109/IWECA.2014.6845785
