Title :
Trace Level Determination of Lewisite in Water by Solid-Phase Microextraction and Gas Chromatography-Mass Spectrometry with Selected Ion-Monitoring
Author :
Zhou Liming ; Zhou Jianmei ; Liu Bo ; Dong Junjun ; Lu Shengli ; Lu Caihong
Author_Institution :
Inst. of Chem. Defence, Beijing
Abstract :
A new analytical procedure was developed for the extraction of Lewisite of chemical warfare agents from water and for derivatization prior to analysis by gas chromatography-mass spectrometry (GC-MS) with selected ion-monitoring. Firstly, lewisite and its degradation products 2-chlorovinylarsonous acid (CVAA) or 2-chlorovinylarsenous oxide(CVAO) or 2-chlorovinylarsonic acid (CVAOA) were derivatized with the propane- 1,3-dithiol, then SPME with 100 mum polydimethylsiloxane (PDMS) and analyzed. The experimental results indicated that the recoveries were more than 95%, the lowest detected concentration is 0.0002 mg/L, and the relative standard deviation of seven injections is 3.2%. This method could satisfy the requirements for the destruction of abandoned chemical weapons by Japan in China.
Keywords :
chemical hazards; chemical variables measurement; chromatography; explosions; mass spectroscopic chemical analysis; spectrochemical analysis; weapons; 2-chlorovinylarsenous oxide; 2-chlorovinylarsonic acid; 2-chlorovinylarsonous acid; Lewisite; SPME; abandoned chemical weapon destruction; chemical warfare agent; gas chromatography-mass spectrometry; polydimethylsiloxane; propane-1,3-dithiol; selected ion-monitoring; solid-phase microextraction; trace level determination; Chemical analysis; Chemical compounds; Degradation; MONOS devices; Optical fiber devices; Optical fiber testing; Spectroscopy; Temperature; Water pollution; Weapons;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
DOI :
10.1109/ICBBE.2008.1152
