Title :
Application of a 3-D ischemic heart model derived from MRI data to the simulation of the electrical activity of the heart
Author :
Stalidis, G. ; Maglaveras, N. ; Dimitriadis, A. ; Pappas, C. ; Strintzis, M. ; Efstratiadis, SN
Author_Institution :
Aristotelian Univ. of Thessaloniki, Greece
Abstract :
The propagation of the electrical activity of the heart is simulated over regions containing infarcted tissue. The method is applied to patients suffering from ischemia, in order to study the impact of the injury on the electrical function of the heart. The spatial distribution of the infarcted tissue and the shape of the endocardial and the epicardial surfaces are derived from MRI data using a semiautomatic method based on 3D Fourier parametric modeling. A 2D grid is then constructed which represents a selected part of the epicardial surface and contains information about the condition of the tissue. This grid is used as input to the simulation algorithm which estimates the ionic currents over time and the propagation of the electric impulse.
Keywords :
bioelectric phenomena; biomedical NMR; cardiology; medical image processing; physiological models; 2D grid; 3-D ischemic heart model; 3D Fourier parametric modeling; MRI data; electric impulse propagation; endocardial surface; epicardial surface; heart electrical activity simulation; infarcted tissue; injury effects; ionic currents estimation; ischemia patients; semiautomatic method; simulation algorithm; tissue condition information; Deformable models; Heart; Injuries; Ischemic pain; Magnetic resonance imaging; Medical simulation; Parametric statistics; Rough surfaces; Surface fitting; Surface roughness;
Conference_Titel :
Computers in Cardiology, 1996
Conference_Location :
Indianapolis, IN, USA
Print_ISBN :
0-7803-3710-7
DOI :
10.1109/CIC.1996.542540
