Signal analysis with Zetasizer on the effect of Poly (Ethylene Glycol) (PEG) to stabilize and unify colloidal gold nanoparticles

Author

Chin, G.F. ; Misran, M. ; Tang, P.Y. ; Lee, P.F.

Author_Institution

Dept. of Mechatron. & Biomed. Eng., Univ. Tunku Abdul, Kuala Lumpur, Malaysia

fYear

2012

Firstpage

513

Lastpage

517

Abstract

This paper reports a study on the effect of the Poly (Ethylene Glycol) (PEG) on the stability and uniformity of the colloidal gold nanoparticles. Sodium Borohydride (NaBH₄) and Trisodium Citrate (Na₃C₆H₅O₇) were utilized as the reducing agents to produce gold nanoparticles in this paper. Comparison of the two reducing agents has showed the Na₃C₆H₅O₇ produces more stable gold nanoparticles solution. With the PEG1000, the gold nanoparticles showed obviously higher uniformity, which produce a desirable monodispersed gold nanoparticles solution.

Keywords

colloids; gold; nanofabrication; nanomedicine; nanoparticles; polymers; Au; Na3C6H5O7; NaBH4; PEG1000; Zetasizer; colloidal gold nanoparticle stabilisation; colloidal gold nanoparticle uniformity; monodispersed gold nanoparticle solution; poly(ethylene glycol) effects; reducing agents; signal analysis; sodium borohydride; trisodium citrate; Drug delivery; Gold; Microscopy; Nanobioscience; Nanoparticles; Thermal stability; Tumors; Gold nanoparticles; PEG; monodispersed; stability; uniform;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Engineering (ICoBE), 2012 International Conference on

Conference_Location

Penang

Print_ISBN

978-1-4577-1990-5

Type

conf

DOI

10.1109/ICoBE.2012.6179071

Filename

6179071