Title :
Some consistent information from 1H-NMR relaxation data of biological tissues and experimental models
Author :
Lendinara, Laura ; Fantazzini, Paola ; Novello, Francesco ; Cucchi, M. Cristina ; Lazzari, Maurizio
Author_Institution :
Dept. of Phys., Bologna Univ., Italy
Abstract :
A multiexponentiality analysis of the 1H spin-spin and spin-lattice relaxation curves at 20 MHz of rat and human tissues is performed by iterative fitting procedures. Liver and thyroid biopsies from patients affected by various diseases and liver samples from Wistar rats in narrow and wide altered physiological conditions are investigated. The behavior of the multiexponential relaxation parameters are discussed on the basis of the results of a 2-D nuclear magnetic resonance (NMR) time correlation analysis of water content, metabolically induced alterations, and changes at the cellular level
Keywords :
biomagnetism; nuclear spin-lattice relaxation; proton magnetic resonance; 20 MHz; 2D NMR time correlation analysis; 1H spin-lattice relaxation; 1H spin-spin relaxation; Wistar rats; biological tissues; cellular level changes; experimental models; human tissues; iterative fitting procedures; liver; metabolically induced alterations; multiexponentiality analysis; thyroid; water content; Biological tissues; Humans; In vitro; Liver; Muscles; Nuclear magnetic resonance; Protons; Shape; Solids; Solvents;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.95885
