Title :
A 2D segmentation algorithm for the analisys of TBY-2 cells
Author :
De Marco, Mariangela ; Locato, Vittoria ; Soda, Paolo ; Vollero, Luca
Author_Institution :
CIR - Centro Integrato di Ricerca, Univ. Campus Bio-Medico di Roma, Rome, Italy
Abstract :
TBY-2 cells are widely used in several applications and in particular in the study of programmed cell-death (PCD). However, automatic or semi-automatic computer-based tools supporting the specialist during the measurement process are still missing. In this paper we propose and test a semi-automatic tool for the segmentation of TBY-2 cell and the measurement of cytosol area. The algorithm has been designed in order to be easy to use and to have low complexity. Results obtained on a database of TBY-2 cells confirm that the algorithm can be effectively used by specialists in their daily work.
Keywords :
biology computing; botany; cellular biophysics; image segmentation; 2D segmentation algorithm; TBY-2 cell analysis; automatic computer-based tools; cytosol area measurement; programmed cell-death; semi-automatic computer-based tools; Algorithm design and analysis; Animals; Image color analysis; Image segmentation; Manuals; Measurement; Three dimensional displays;
Conference_Titel :
Computer-Based Medical Systems (CBMS), 2010 IEEE 23rd International Symposium on
Conference_Location :
Perth, WA
Print_ISBN :
978-1-4244-9167-4
DOI :
10.1109/CBMS.2010.6042651