A parallelizable technique for 3D simulations of cardiac electrical propagation based on sub-cellular physiology

A new methodology was developed for numerical simulations of cardiac electrical activity. The technique allows larger and more complex models to be examined while retaining sub-cellular resolution and physiology. The cable model of cardiac tissue assumes a network of passive resistances linking ionic and capacitive membrane elements. This model was adapted for implementation in high performance parallel and vector computing environments. The methods were then expanded to allow for modeling of three dimensional geometries. Preliminary simulations show qualitative agreement with the authors´ previous studies, providing validation of the revised techniques