Title :
Application of model quality evaluation to systems biology
Author :
Falugi, Paola ; Giarré, Laura
Author_Institution :
SUPELEC, Gif-sur-Yvette
Abstract :
Application of model quality evaluation to the quasispecies models is presented. These models are useful for the analysis of the DNA and RNA evolution and for the description of the population dynamics of viruses and bacteria. An estimate of the parameters together with their interval of variability is computed and the quality evaluation is tested on the basis of the model prediction error capability.
Keywords :
DNA; biochemistry; evolution (biological); genetics; microorganisms; molecular biophysics; reaction kinetics; DNA evolution; RNA evolution; bacteria; chemical reaction network; model prediction error; model quality evaluation; quasispecies models; systems biology; viruses population dynamics; Biological system modeling; Biology computing; DNA; Evolution (biology); Microorganisms; Parameter estimation; RNA; Systems biology; Testing; Viruses (medical);
Conference_Titel :
Communications, Control and Signal Processing, 2008. ISCCSP 2008. 3rd International Symposium on
Conference_Location :
St Julians
Print_ISBN :
978-1-4244-1687-5
Electronic_ISBN :
978-1-4244-1688-2
DOI :
10.1109/ISCCSP.2008.4537206
