Title :
Microparticulate focal drug delivery to the peripheral and central nervous systems
Author :
Kohane, Daniel S.
Author_Institution :
Pediatric Intensive Care Unit, Harvard Med. Sch., Boston, MA, USA
Abstract :
Focal drug delivery using microparticles holds great promise in treating specific disorders in the peripheral and central nervous systems. In the peripheral nervous system, controlled release technology is readily applicable to providing prolonged nerve blockade, while in the central nervous system there is increasing interest in its uses for epilepsy and movement disorders.
Keywords :
biomechanics; drug delivery systems; neurophysiology; analgesia; anticonvulsant; central nervous system; epilepsy; microparticles; microparticulate focal drug delivery; microsphere; movement disorders; peripheral nervous system; prolonged nerve blockade; Animals; Central nervous system; Chemical technology; Drug delivery; Epilepsy; Medical treatment; Nervous system; Pain; Pharmaceutical technology; Safety;
Conference_Titel :
Bioengineering Conference, 2003 IEEE 29th Annual, Proceedings of
Print_ISBN :
0-7803-7767-2
DOI :
10.1109/NEBC.2003.1216121
