DocumentCode
1710621
Title
Transdermal drug delivery: an assessment of skin impedance models
Author
Coston, Anthony F. ; Li, John K -J
Author_Institution
Instrum. & Electron., Ethicon Inc., Somerville, NJ, USA
fYear
2003
Firstpage
319
Lastpage
320
Abstract
The variability found in skin impedance can significantly influence the effectiveness of Transdermal Drug Delivery. In order to optimize drug delivery, skin impedance frequency response must be considered. Several electrical models for skin impedance are presented in an attempt to understand the "status quo" and to provide suggestions for future improvements. Transdermal drug delivery, using iontophoresis, cannot be optimized until all facets of skin impedance are thoroughly understood.
Keywords
bioelectric phenomena; drug delivery systems; electrophoresis; frequency response; skin; drug delivery optimization; iontophoresis; simple diffusion; skin electrical models; skin impedance models; transdermal drug delivery; Capacitance; Circuits; Drug delivery; Electrical resistance measurement; Frequency; Immune system; Impedance; Polarization; Skin; Steady-state;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioengineering Conference, 2003 IEEE 29th Annual, Proceedings of
Print_ISBN
0-7803-7767-2
Type
conf
DOI
10.1109/NEBC.2003.1216124
Filename
1216124
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