Title :
Enzyme-based nanocomposites: Using nature to ward off emerging threats
Author :
Mehta, Krunal K. ; Pangule, Ravindra C. ; Paskaleva, Elena E. ; Mundra, Ruchir V. ; Dordick, Jonathan S. ; Kane, Ravi S.
Author_Institution :
Howard P. Isermann Dept. of Chem. & Biol. Eng., Rensselaer Polytech. Inst., Troy, NY, USA
Abstract :
We report the development of novel antimicrobial nanocomposites incorporating enzymes. We also describe approaches to identify novel cell lytic enzymes that can target pathogens with high specificity under ambient environmental conditions.
Keywords :
antibacterial activity; biochemistry; biomedical materials; cellular biophysics; diseases; enzymes; nanocomposites; nanomedicine; ambient environmental conditions; antimicrobial nanocomposites; cell lytic enzymes; emerging threats; enzyme-based nanocomposites; nature; pathogens; Biochemistry; Films; Microorganisms; Nanocomposites; Pathogens; Bacillus anthracis; antimicrobial film; autolysins; bacteriolytic enzymes; carbon nanotube; lysostaphin; methicillin-resistant Staphylococcus aureus (MRSA); nanocomposite; phage lysins; spore killing;
Conference_Titel :
Bioengineering Conference (NEBEC), 2014 40th Annual Northeast
Conference_Location :
Boston, MA
DOI :
10.1109/NEBEC.2014.6972874
