Title :
Modelling and Implementation of a Novel SPR Biointerface for Time-Effective Detection of Sepsis Biomarkers
Author :
Hoa, X.D. ; Kirk, A.G. ; Tabrizian, Maryam
Author_Institution :
McGill Univ., Montreal
Abstract :
Early and effective diagnosis of sepsis is made possible with the detection of specific biomarkers. This requires the design of a specific and sensitive immunoassay biointerface. In this proceeding, we discussed the modelling and implementation of a novel surface plasmon resonance (SPR) interface featuring nano-gratings and selective surface biochemical functionalization. Simulation suggests that such an interface enhances the sensitivity of SPR systems.
Keywords :
biochemistry; diseases; medical computing; nanobiotechnology; patient diagnosis; surface plasmon resonance; SPR biointerface; immunoassay biointerface; nanogratings; sepsis biomarker; sepsis diagnosis; surface biochemical functionalization; surface plasmon resonance interface; time-effective detection; Biomarkers; Biomedical engineering; Biosensors; Corrugated surfaces; Immune system; Medical treatment; Optical surface waves; Plasmons; Resonance; Surface treatment;
Conference_Titel :
Computer Architecture for Machine Perception and Sensing, 2006. CAMP 2006. International Workshop on
Conference_Location :
Montreal, Que.
Print_ISBN :
978-1-4244-0685-2
Electronic_ISBN :
978-1-4244-0686-9
DOI :
10.1109/CAMP.2007.4350345
