Modelling and Implementation of a Novel SPR Biointerface for Time-Effective Detection of Sepsis Biomarkers

Author

Hoa, X.D. ; Kirk, A.G. ; Tabrizian, Maryam

Author_Institution

McGill Univ., Montreal

fYear

2006

Firstpage

30

Lastpage

33

Abstract

Early and effective diagnosis of sepsis is made possible with the detection of specific biomarkers. This requires the design of a specific and sensitive immunoassay biointerface. In this proceeding, we discussed the modelling and implementation of a novel surface plasmon resonance (SPR) interface featuring nano-gratings and selective surface biochemical functionalization. Simulation suggests that such an interface enhances the sensitivity of SPR systems.

Keywords

biochemistry; diseases; medical computing; nanobiotechnology; patient diagnosis; surface plasmon resonance; SPR biointerface; immunoassay biointerface; nanogratings; sepsis biomarker; sepsis diagnosis; surface biochemical functionalization; surface plasmon resonance interface; time-effective detection; Biomarkers; Biomedical engineering; Biosensors; Corrugated surfaces; Immune system; Medical treatment; Optical surface waves; Plasmons; Resonance; Surface treatment;

fLanguage

English

Publisher

ieee

Conference_Titel

Computer Architecture for Machine Perception and Sensing, 2006. CAMP 2006. International Workshop on

Conference_Location

Montreal, Que.

Print_ISBN

978-1-4244-0685-2

Electronic_ISBN

978-1-4244-0686-9

Type

conf

DOI

10.1109/CAMP.2007.4350345

Filename

4350345