Title :
Microfluidic device for immobilization of bio-vesicles towards controlled on-chip electrofusion
Author :
Ziegler, D. ; Coque, Ph ; Tixier-Mita, A. ; Tresset, G. ; Fujita, H. ; Takeuchi, S.
Author_Institution :
CIRMM/IIS, Univ. of Tokyo, Japan
Abstract :
We describe a microfluidic device that combines microfluidic and electrical manipulation of cells or artificial vesicles in order to perform well controlled electrofusion. Primary vesicles are immobilized by suction onto a silicon array of microholes. Secondary vesicles are aligned on the first ones using dielectrophoresis.
Keywords :
cellular biophysics; electrophoresis; laboratory techniques; microfluidics; micromachining; micromanipulators; silicon; Si; bio-vesicle immobilization; device fabrication; dielectrophoresis; electrical manipulation; microfluidic device; microfluidic manipulation; microholes; on-chip electrofusion; Biological processes; Biomembranes; Cells (biology); Containers; Dielectrophoresis; In vivo; Microfluidics; Monitoring; Organisms; Silicon;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems, 2005. Digest of Technical Papers. TRANSDUCERS '05. The 13th International Conference on
Print_ISBN :
0-7803-8994-8
DOI :
10.1109/SENSOR.2005.1496430
