Title :
Planar microcoil-based magnetic resonance imaging of cells
Author :
Massin, C. ; Eroglu, S. ; Vincent, F. ; Gimi, B.S. ; Besse, P.-A. ; Magin, R.L. ; Popovic, R.S.
Author_Institution :
Inst. of Microelectron. & Microsyst., Swiss Fed. Inst. of Technol., Lausanne, Switzerland
Abstract :
We report magnetic resonance images of biological cells and cellular aggregates obtained in vitro using high-Q factor microfabricated planar coils at 500 MHz. An image of a /spl sim/1 mm diameter frog oocyte is acquired using a 500-/spl mu/m microcoil, high-resolution images of intact mouse pancreatic islets(/spl sim/100 /spl mu/m size) are successfully acquired for the first time. Due to their planer nature, compatibility with on-chip cell culturing methods and enhanced sensitivity for microscopic samples, micromachined coils will prove essential to perform further Magnetic Resonance studies at the cellular level.
Keywords :
Q-factor; biomagnetism; biomedical MRI; coils; image resolution; magnetic resonance imaging; micromechanical devices; sensitivity; 1 mm; 100 micron; 200 micron; 500 MHz; 500 micron; Q factor; biological cells; intact mouse pancreatic islets; microfabricated planer coils; micromachined coils; planar microcoil-based magnetic resonance imaging; sensitivity; Aggregates; Biological cells; Coils; In vitro; Magnetic force microscopy; Magnetic resonance; Magnetic resonance imaging; Metalworking machines; Mice; Pancreas;
Conference_Titel :
TRANSDUCERS, Solid-State Sensors, Actuators and Microsystems, 12th International Conference on, 2003
Conference_Location :
Boston, MA, USA
Print_ISBN :
0-7803-7731-1
DOI :
10.1109/SENSOR.2003.1216928
