Title :
Continuous paramagnetophoretic microseparator for blood cells
Author :
Ki-Ho Han ; Landers, J.P. ; Frazier, A.B.
Author_Institution :
Sch. of Electr. & Comput. Eng., Georgia Inst. of Technol., Atlanta, GA, USA
Abstract :
This paper presents a continuous paramagnetophoretic (PMP) microseparator for directly separating blood cells from whole blood by using a high gradient magnetic separation (HGMS) method. For high magnetic separation force, the present PMP separator is fabricated by microfabrication technology, and directly separates red and white blood cells from whole blood based on their magnetic properties. The theoretical model of the PMP microseparator is derived, and simulated values are compared with calculated values. A quantitative analysis using a hemocytometer shows that 92% of red blood cells are separated from whole blood by the present PMP microseparator.
Keywords :
biomagnetism; blood; magnetic forces; magnetic separation; micromechanical devices; blood cell separation; continuous paramagnetophoretic microseparator; hemocytometer; high gradient magnetic separation method; magnetic properties; magnetic separation force; microfabrication technology; red blood cells; white blood cells; Cells (biology); Magnetic analysis; Magnetic fields; Magnetic particles; Magnetic separation; Magnetostatics; Particle separators; Portable media players; Red blood cells; Wire;
Conference_Titel :
TRANSDUCERS, Solid-State Sensors, Actuators and Microsystems, 12th International Conference on, 2003
Conference_Location :
Boston, MA, USA
Print_ISBN :
0-7803-7731-1
DOI :
10.1109/SENSOR.2003.1216994
