Title :
Electro-hydrodynamic modeling of electrospray ionization: CAD for a /spl mu/fluidic device-mass spectrometer interface
Author :
Jun Zeng ; Sobek, D. ; Korsmeyer, T.
Author_Institution :
Coventor, Inc., Cambridge, MA, USA
Abstract :
We report on full-dimensional, multi-phase, electro-hydrodynamic simulations of electrospray dynamics and our simulation method derived from Melcher & Taylor´s leaky dielectric fluids model. The method is first validated via the Melcher-Taylor apparatus and corresponding analytical solution, and then applied to understanding the formation of Taylor cones, a key issue in designing a /spl mu/fluidic device with an integrated mass-spectrometer interface. The simulation results show excellent agreement with the Melcher-Taylor solution. The transient full-dimensional simulation of Taylor cone formation shown here is believed the first published result of this kind. Experiment results in electrospray dynamics are presented for qualitative comparison.
Keywords :
CAD; Navier-Stokes equations; dielectric liquids; electrical conductivity; electrohydrodynamics; electrostatic devices; fluidic devices; mass spectrometers; microfluidics; /spl mu/fluidic device; CAD; Melcher-Taylor solution; Taylor cones; Taylor leaky dielectric fluids model; electro-hydrodynamic modeling; electrospray dynamics; electrospray ionization; integrated mass-spectrometer interface; simulations; Dielectrics; Electrochemical impedance spectroscopy; Electronic mail; Fluid dynamics; Hydrodynamics; Ionization; Laboratories; Mass spectroscopy; Navier-Stokes equations; Stress;
Conference_Titel :
TRANSDUCERS, Solid-State Sensors, Actuators and Microsystems, 12th International Conference on, 2003
Conference_Location :
Boston, MA, USA
Print_ISBN :
0-7803-7731-1
DOI :
10.1109/SENSOR.2003.1217005
