• DocumentCode
    1741405
  • Title

    Beam-orientation optimisation of IMRT: clinical application to parotid gland tumours

  • Author

    Rowbottom, Carl ; Nutting, Chris ; Webb, S.

  • Author_Institution
    NOMOS Corp., Sewickley, PA, USA
  • Volume
    1
  • fYear
    2000
  • fDate
    2000
  • Firstpage
    470
  • Abstract
    The potential of IMRT to reduce toxicity was investigated. Initially, a treatment plan was set-up on the CORVUS1 inverse treatment planning system using nine equi-spaced beams. The goal of the inverse plan was to reduce the dose to the cochlea and the oral cavity compared to the conformal wedged pair technique. The plan reduced the dose to the cochlea and to a lesser extent reduced the volume of the oral cavity receiving high-dose, and also improved the PTV homogeneity. Unfortunately, compared to the conformal wedged pair technique, the IMRT plan greatly increased the dose to the contralateral parotid gland with 73% of the OAR receiving dose in excess of 6 Gy
  • Keywords
    biological organs; dosimetry; radiation therapy; tumours; 6 gray; beam-orientation optimisation; clinical application; cochlea dose reduction; conformal wedged pair technique; contralateral parotid gland; equispaced beams; homogeneity improvement; intensity modulated radiotherapy; inverse plan; oral cavity; parotid gland tumours; toxicity reduction; Cost function; Deafness; Glands; Mouth; Optimization methods; Size control; Spinal cord; Surgery; Tumors;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2000. Proceedings of the 22nd Annual International Conference of the IEEE
  • Conference_Location
    Chicago, IL
  • ISSN
    1094-687X
  • Print_ISBN
    0-7803-6465-1
  • Type

    conf

  • DOI
    10.1109/IEMBS.2000.900778
  • Filename
    900778