DocumentCode :
1745060
Title :
Optimizing visualization of breast microcalcifications
Author :
Anderson, M.E. ; Soo, M.S.C. ; Trahey, G.E.
Author_Institution :
Dept. of Biomed. Eng., Rochester Univ., NY, USA
Volume :
2
fYear :
2000
fDate :
36800
Firstpage :
1315
Abstract :
We combine our results from a series of clinical, experimental, and analytical studies to present comprehensive recommendations for the improved visualization of breast microcalcifications with ultrasound. Such improved visualization would extend the utility of breast ultrasound in guiding biopsy and in the differentiation of breast lesions, particularly in the mammographically dense breast. The in vivo clinical data used to inform our recommendations were collected with a Siemens Elegra scanner and 7.5 and 10 MHz probes, and include breast tissue backscatter measurements (N=16), channel-by-channel RF echo data from microcalcifications (N=7), and measurements of speckle statistics in breast tissues (N=16). Our measurements of speckle statistics suggest that echoes from these tissues do not exhibit fully-developed speckle (SNR=1.3-1.4 vs. 1.85 control, 1.91 theoretical). Imaging parameters considered include sound speed error, phase aberration, probe frequency, spatial resolution, and speckle reduction by compounding. We compare the relative impact of these parameters on visualization using, among other performance metrics, the area under the ROC curve. We identify the overall performance trends so demonstrated in the interest of guiding improvements in breast imaging with ultrasound
Keywords :
biomedical ultrasonics; mammography; medical image processing; speckle; tumours; 10 MHz; 7.5 MHz; ROC curve; breast microcalcifications; breast ultrasound; channel-by-channel RF echo data; image guided biopsy; in vivo clinical data; lesions differentiation; mammographically dense breast; phase aberration; probe frequency; sound speed error; spatial resolution; speckle reduction; speckle statistics; tissue backscatter; visualization optimisation; Backscatter; Breast biopsy; Breast tissue; Data visualization; In vivo; Lesions; Probes; Speckle; Statistics; Ultrasonic imaging;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Ultrasonics Symposium, 2000 IEEE
Conference_Location :
San Juan
ISSN :
1051-0117
Print_ISBN :
0-7803-6365-5
Type :
conf
DOI :
10.1109/ULTSYM.2000.921565
Filename :
921565
Link To Document :
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