• DocumentCode
    1754518
  • Title

    Monte Carlo Latching Studies of Prompt-Gamma Detection During Hadrontherapy

  • Author

    Chin, M.P.W. ; Cerutti, F. ; Ferrari, A. ; Ortega, P.G. ; Sala, P.R.

  • Author_Institution
    Eur. Lab. for Particle Phys., CERN, Geneva, Switzerland
  • Volume
    61
  • Issue
    5
  • fYear
    2014
  • fDate
    Oct. 2014
  • Firstpage
    2540
  • Lastpage
    2546
  • Abstract
    Proton and carbon therapies of a human brain were simulated using FLUKA, with particular emphasis on treatment monitoring using the prompt gamma method where activities of the source proton/carbon in the patient´s body are to be extracted from the positional profile of exit photons. Tissue heterogeneity ranging from hydrogen to zinc was represented in a VIP-Man anthropomorphic voxel phantom. Each photon exiting the head was scored with ancestry attributes such as the particle type of its parent, the originating collision type and site. These data, not accessible via physical detectors, were analysed to characterise the escaping photons, delineating signal from noise according to the gamma origin and scatter history. Combinations of energy, geometry, time and angle filters, aided by raytracing, were studied for the optimal compromise between a sufficiently featured exit profile and a statistically adequate count. These will be put in context with ongoing research in the field; our perspective for the prompt gamma method will be discussed in detail.
  • Keywords
    Monte Carlo methods; biological tissues; brain; gamma-ray detection; neurophysiology; phantoms; radiation therapy; ray tracing; FLUKA; Monte Carlo latching; VIP-Man anthropomorphic voxel phantom; angle filter; carbon therapy; escaping photons; exit photon positional profile; hadron therapy; human brain; physical detectors; prompt-gamma detection; proton therapy; ray tracing; time filter; tissue heterogeneity; treatment monitoring; Carbon; Neutrons; Particle beams; Phantoms; Photonics; Protons; Radiation effects; Carbon therapy; FLUKA; Monte Carlo; hadrontherapy; prompt gamma; proton therapy; treatment monitoring;
  • fLanguage
    English
  • Journal_Title
    Nuclear Science, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9499
  • Type

    jour

  • DOI
    10.1109/TNS.2014.2356553
  • Filename
    6912027