DocumentCode
1755061
Title
Miniaturized Passive Hydrogel Check Valve for Hydrocephalus Treatment
Author
Schwerdt, Helen N. ; Bristol, Ruth E. ; Junseok Chae
Author_Institution
Dept. of Electr. Eng., Arizona State Univ., Tempe, AZ, USA
Volume
61
Issue
3
fYear
2014
fDate
41699
Firstpage
814
Lastpage
820
Abstract
Improvements in cerebrospinal fluid (CSF) draining techniques for treatment of hydrocephalus are urgently sought after to substitute for current CSF shunts that are plagued by high failure rates. The passive check valve aims to restore near natural CSF draining operations while mitigating possible failure mechanisms caused by finite leakage or low resilience that frequently constrain practical implementation of miniaturized valves. A simple hydrogel diaphragm structures core passive valve operations and enforce valve sealing properties to substantially lower reverse flow leakage. Experimental measurements demonstrate realization of targeted cracking pressures (PT ≈ 20-110 mmH2O) and operation at -800 <; ΔP <; 600 mmH2O without observable degradation or leakage.
Keywords
biomechanics; brain; cracks; diaphragms; fracture; hydrogels; medical disorders; neurophysiology; patient treatment; cerebrospinal fluid draining techniques; core passive valve operations; current CSF shunts; enforce valve sealing properties; failure mechanisms; high failure rates; hydrocephalus treatment; low reverse flow leakage; miniaturized passive hydrogel check valve; miniaturized valves; natural CSF draining operations; simple hydrogel diaphragm structures; targeted cracking pressure realization; Biomembranes; Fluids; Iterative closest point algorithm; Silicon; Substrates; Valves; Check valve; hydrogel; implantable microsystem; intracranial pressure (ICP) regulation; passive valve;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/TBME.2013.2290291
Filename
6661354
Link To Document