Numerical Modeling of MR Angiography for Quantitative Validation of Image-Driven Assessment of Carotid Stenosis

Author

Klepaczko, Artur ; Materka, Andrzej ; Szczypinski, Piotr ; Strzelecki, Michal

Author_Institution

Med. Electron. Div., Lodz Univ. of Technol., Lodz, Poland

Volume

62

Issue

3

fYear

2015

fDate

42156

Firstpage

619

Lastpage

627

Abstract

In this paper we present a numerical framework for validating methods of quantitative analysis of non-invasive MR angiography imaging protocols such as Time-of-Flight (ToF) and Phase Contrast Angiography (PCA). Our study is motivated by the need to reliably and objectively verify blood flow and geometry measurements derived from image data. Both factors are important predictors in diagnosing of carotid artery stenosis. Credibility of the tested image processing methods is verified by comparing their results against reference models designed using integrated flow and MRA imaging simulator.

Keywords

biomedical MRI; blood vessels; diseases; haemodynamics; medical image processing; MR angiography; MRA imaging simulator; PCA; blood flow; carotid artery stenosis diagnosis; image processing; image-driven assessment; integrated flow; numerical modeling; phase contrast angiography; time-of-flight angiography; Angiography; Blood; Computational modeling; Magnetization; Mathematical model; Numerical models; Carotid artery stenosis; MRI simulation; computational fluid dynamics; image-based medical diagnosis; magnetic resonance angiography; vessel segmentation;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/TNS.2015.2433925

Filename

7118757