Title :
Peptide-Functionalized Quantum Dot Biosensors
Author :
Nagy, Akos ; Gemmill, Kelly Boeneman ; Delehanty, James B. ; Medintz, Igor L. ; Sapsford, Kim E.
Author_Institution :
Div. of Biol., U.S. Food & Drug Adm., Silver Spring, MD, USA
Abstract :
Quantum dot (QD) nanomaterials have a number of electro-optical properties that make them ideal for biosensing applications. QDs combined with peptides have been used for both targeting and sensing applications, however this review will focus specifically on peptide-functionalized QD biosensors, whose signal transduction occurs through active modulation of the QD photoluminescent properties.
Keywords :
biosensors; nanobiotechnology; nanostructured materials; organic compounds; photoluminescence; reviews; semiconductor quantum dots; QD photoluminescent properties; biosensing applications; electro-optical properties; peptide-functionalized QD biosensors; peptide-functionalized quantum dot biosensors; quantum dot nanomaterials; review; signal transduction; Biosensors; Inhibitors; Nanoparticles; Peptides; Proteins; Substrates; Biosensor; Förster resonance energy transfer (FRET); bioluminescence resonance energy transfer (BRET); peptide; protease; quantum dot (QD);
Journal_Title :
Selected Topics in Quantum Electronics, IEEE Journal of
DOI :
10.1109/JSTQE.2013.2284427
