A microsystem for magnetic immunoassay towards protein toxins detection

This work focuses on the circuit and system implementation of a magnetic immunoassay based microsystem platform to be used as sensor terminal for detecting protein toxins in environment. Three main challenges facing this work-the design of a high performance sensor, the packaging technique and the design of integrated circuit are introduced. Planar microcoil array fabricated both on silicon substrate and polymer substrate are exploited as sensor of magnetic particles, whereas microchannel and ultra thin bottom microplate for traditional ELISA was used for reagents, correspondingly. Simulation results of two detection circuits prove that our system is able to detect magnetic particles in different volumes, thus the proposed microsystem has potential for medical diagnostics, food pathogen detection or water analysis.