Title :
Automated single molecule nucleic acid detection with a waveguide chip
Author :
Parks, J.W. ; Zempoaltecatl, L. ; Mathies, R.A. ; Hawkins, A.R. ; Schmidt, Heidemarie
Author_Institution :
Sch. of Eng., Univ. of California, Santa Cruz, Santa Cruz, CA, USA
Abstract :
Lambda DNA (λ-DNA) molecules were labeled with SYBR Gold nucleic acid stain using a PDMS-based programmable microfluidic chip (Automaton). Single DNA molecules were detected in a vertically integrated liquid-core waveguide chip.
Keywords :
DNA; microfluidics; molecular biophysics; λ-DNA molecules; Lambda DNA molecules; PDMS-based programmable microfluidic chip; SYBR gold nucleic acid stain; automated single molecule nucleic acid detection; single DNA molecules; vertical integrated liquid-core waveguide chip; waveguide chip; Automata; DNA; Educational institutions; Fluorescence; Liquid waveguides; Microfluidics; Optical waveguides;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2014 Conference on
Conference_Location :
San Jose, CA
