Title :
Surface-enhanced raman scattering immuno-assay using diatom frustules
Author :
Jing Yang ; Fanghui Ren ; Zhen Le ; Campbell, Joe ; Rorrer, Gregory L. ; Wang, Alan X.
Author_Institution :
Sch. of Electr. Eng. & Comput. Sci., Oregon State Univ., Corvallis, OR, USA
Abstract :
An immunoassay based on surface-enhanced Raman scattering has been developed using diatom frustules to detect antigens with high sensitivity. It was found that the diatom frustules provide 6× higher sensitivity than traditional glass substrates.
Keywords :
Raman spectra; biomedical equipment; cellular biophysics; molecular biophysics; optical sensors; proteins; antigen detection; diatom frustules; surface-enhanced Raman scattering immunoassay; Glass; Immune system; Mice; Nanoparticles; Raman scattering; Sensors; Substrates;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2014 Conference on
Conference_Location :
San Jose, CA
