Title : 
Spectral band selection for mitosis detection in histopathology
         
        
            Author : 
Irshad, Humayun ; Gouaillard, Alexandre ; Roux, Ludovic ; Racoceanu, Daniel
         
        
            Author_Institution : 
Univ. Joseph Fourier, Grenoble, France
         
        
        
            fDate : 
April 29 2014-May 2 2014
         
        
        
        
            Abstract : 
This study aims at evaluating the accuracy of mitosis detection on multispectral histopathological images by developing a solution specifically designed to take advantage of multi-spectral information. The proposed framework includes a selection of spectral bands and focal plane, detection of candidate mitotic regions, computation of morphological & mul-tispectral statistical features (MMSF) and study of different state-of-the-art classification methods for mitosis classification. This framework achieved 74% TPR, 76% PPV and 74% F-Measure on MITOS dataset. Our results indicate that selected multispectral bands contain discriminant information for mitotic figures, being therefore a very promising exploration area to improve the quality of the diagnosis assistance in histopathology.
         
        
            Keywords : 
biological tissues; biomedical optical imaging; feature extraction; focal planes; image classification; medical image processing; F-Measure; MITOS dataset; MMSF; diagnosis assistance; discriminant information; focal plane; histopathology; mitosis classification; mitosis detection; morphological multispectral statistical features; multispectral histopathological images; spectral band selection; Absorption; Breast cancer; Feature extraction; Frequency modulation; Mutual information; Redundancy; histopathology; mitosis detection; multispectral images; spectral band selection;
         
        
        
        
            Conference_Titel : 
Biomedical Imaging (ISBI), 2014 IEEE 11th International Symposium on
         
        
            Conference_Location : 
Beijing
         
        
        
            DOI : 
10.1109/ISBI.2014.6868110