• DocumentCode
    1772208
  • Title

    Spectral band selection for mitosis detection in histopathology

  • Author

    Irshad, Humayun ; Gouaillard, Alexandre ; Roux, Ludovic ; Racoceanu, Daniel

  • Author_Institution
    Univ. Joseph Fourier, Grenoble, France
  • fYear
    2014
  • fDate
    April 29 2014-May 2 2014
  • Firstpage
    1279
  • Lastpage
    1282
  • Abstract
    This study aims at evaluating the accuracy of mitosis detection on multispectral histopathological images by developing a solution specifically designed to take advantage of multi-spectral information. The proposed framework includes a selection of spectral bands and focal plane, detection of candidate mitotic regions, computation of morphological & mul-tispectral statistical features (MMSF) and study of different state-of-the-art classification methods for mitosis classification. This framework achieved 74% TPR, 76% PPV and 74% F-Measure on MITOS dataset. Our results indicate that selected multispectral bands contain discriminant information for mitotic figures, being therefore a very promising exploration area to improve the quality of the diagnosis assistance in histopathology.
  • Keywords
    biological tissues; biomedical optical imaging; feature extraction; focal planes; image classification; medical image processing; F-Measure; MITOS dataset; MMSF; diagnosis assistance; discriminant information; focal plane; histopathology; mitosis classification; mitosis detection; morphological multispectral statistical features; multispectral histopathological images; spectral band selection; Absorption; Breast cancer; Feature extraction; Frequency modulation; Mutual information; Redundancy; histopathology; mitosis detection; multispectral images; spectral band selection;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Imaging (ISBI), 2014 IEEE 11th International Symposium on
  • Conference_Location
    Beijing
  • Type

    conf

  • DOI
    10.1109/ISBI.2014.6868110
  • Filename
    6868110