A new measurement based approach to the study of biological systems

This paper proposes a new approach to the analysis and design of biological systems. It will be shown that, upon an application of Time-Scale Separation Principle to a nonlinear biochemical system at steady-state, a rational polynomial function relates the chemical characteristics of slow-rate substances. This functional dependency can be determined by a small set of measurements. With the functional dependency in hand, one can impose design constraints, such as limiting values for concentration of product substances, and extract corresponding values for the design parameters. Some important characteristics of this rational polynomial form will be also explored.