DocumentCode
1784879
Title
Improving Kernel-based protein-protein interaction extraction by unsupervised word representation
Author
Lishuang Li ; Rui Guo ; Zhenchao Jiang ; Degen Huang
Author_Institution
Sch. of Comput. Sci. & Technol., Dalian Univ. of Technol., Dalian, China
fYear
2014
fDate
2-5 Nov. 2014
Firstpage
379
Lastpage
384
Abstract
As an important branch of biomedical information extraction, Protein-Protein Interaction extraction (PPIe) from biomedical literatures has been widely researched, and machine learning methods have achieved great success for this task. However, the word feature generally adopted in the existing methods suffers badly from vocabulary gap and data sparseness, weakening the classification performance. In this paper, the unsupervised word representation approach is introduced to address these problems. Three word representation methods are adopted to improve the performance of PPIe: distributed representation, vector clustering and Brown clusters representation. Experimental results show that our method outperforms the state-of-the-art methods on five publicly available corpora.
Keywords
biology computing; molecular biophysics; proteins; unsupervised learning; Brown clusters representation; biomedical information extraction; data sparseness; distributed representation; kernel-based protein-protein interaction extraction; machine learning methods; unsupervised word representation; vector clustering; vocabulary gap; Clustering algorithms; Context; Data mining; Feature extraction; Kernel; Proteins; Vectors; Brown clusters; Protein-Protein Interaction; distributed representation; word representation;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedicine (BIBM), 2014 IEEE International Conference on
Conference_Location
Belfast
Type
conf
DOI
10.1109/BIBM.2014.6999188
Filename
6999188
Link To Document