• DocumentCode
    1791706
  • Title

    Information gateway for integrated pharmacogenomics data- IGIPD

  • Author

    Kumar, Pranaw ; Chintalapati, Janaki ; Neeharika, N. ; Saluja, Payal ; Mangala, N. ; Prahlada Rao, B.B.

  • Author_Institution
    Centre for Dev. of Adv. Comput. (C-DAC), Bangalore, India
  • fYear
    2014
  • fDate
    27-30 Oct. 2014
  • Firstpage
    1
  • Lastpage
    9
  • Abstract
    The current challenge in drug discovery lies in developing personalized drugs as individual genetic makeup respond differently to a particular drug. There are enough evidences of adverse drug reactions because of genetic response towards drugs in drug therapy. The study of these relations between the human genomics and pharmacogenetics emerged into Pharmacogenomics. There are many publicly accessible pharmacogenomic data repositories having large, rapidly changing and complex data. These databases provide information about the drugs, their adverse reactions, chemical formula, information about metabolic pathways, drug targets, disease for which a particular drug is used etc. None of the existing pharmacogenomic databases carry the complete integrated information and hence there is a need to develop a database which integrates data from all the widely used databases.
  • Keywords
    biology computing; data handling; database management systems; drug delivery systems; genomics; IGIPD; adverse drug reactions; drug discovery; drug response; drug therapy; human genomics; information gateway; integrated pharmacogenomics data; personalized drug development; pharmacogenetics; pharmacogenomic databases; Bioinformatics; Chemicals; Databases; Diseases; Drugs; Genomics; Proteins; drug targets; metabolic pathways; pharmacogenetics; pharmacogenomics;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Big Data (Big Data), 2014 IEEE International Conference on
  • Conference_Location
    Washington, DC
  • Type

    conf

  • DOI
    10.1109/BigData.2014.7004385
  • Filename
    7004385