DocumentCode
1791706
Title
Information gateway for integrated pharmacogenomics data- IGIPD
Author
Kumar, Pranaw ; Chintalapati, Janaki ; Neeharika, N. ; Saluja, Payal ; Mangala, N. ; Prahlada Rao, B.B.
Author_Institution
Centre for Dev. of Adv. Comput. (C-DAC), Bangalore, India
fYear
2014
fDate
27-30 Oct. 2014
Firstpage
1
Lastpage
9
Abstract
The current challenge in drug discovery lies in developing personalized drugs as individual genetic makeup respond differently to a particular drug. There are enough evidences of adverse drug reactions because of genetic response towards drugs in drug therapy. The study of these relations between the human genomics and pharmacogenetics emerged into Pharmacogenomics. There are many publicly accessible pharmacogenomic data repositories having large, rapidly changing and complex data. These databases provide information about the drugs, their adverse reactions, chemical formula, information about metabolic pathways, drug targets, disease for which a particular drug is used etc. None of the existing pharmacogenomic databases carry the complete integrated information and hence there is a need to develop a database which integrates data from all the widely used databases.
Keywords
biology computing; data handling; database management systems; drug delivery systems; genomics; IGIPD; adverse drug reactions; drug discovery; drug response; drug therapy; human genomics; information gateway; integrated pharmacogenomics data; personalized drug development; pharmacogenetics; pharmacogenomic databases; Bioinformatics; Chemicals; Databases; Diseases; Drugs; Genomics; Proteins; drug targets; metabolic pathways; pharmacogenetics; pharmacogenomics;
fLanguage
English
Publisher
ieee
Conference_Titel
Big Data (Big Data), 2014 IEEE International Conference on
Conference_Location
Washington, DC
Type
conf
DOI
10.1109/BigData.2014.7004385
Filename
7004385
Link To Document