Microscale cell manipulation by using photodegradable hydrogel

Author

Sugiura, Shinya ; Yanagawa, Fumiki ; Takagi, Toshiyuki ; Sumaru, Kimio ; Kanamori, Toshiyuki ; Tamura, Masato ; Matsui, H.

Author_Institution

Res. Center for Stem Cell Eng., Nat. Inst. of Adv. Ind. Sci. & Technol. (AIST), Tsukuba, Japan

fYear

2014

fDate

10-12 Nov. 2014

Firstpage

1

Lastpage

2

Abstract

In this work, we present a novel photocleavable crosslinker to form photodegradable hydrogel through one step reaction by mixing with biocompatible polymers containing amino moieties (amino-terminated tetra-arm poly(ethylene glycol) or gelatin). Our new photocleavable crosslinker can be utilized as potentially versatile and convenient material to prepare photodegradable hydrogels with amino terminated biocompatible polymers. We present a couple of cell manipulation technique using the photodegradable hydrogels prepared with our photocleavable crosslinker.

Keywords

biochemistry; cellular biophysics; gelatin; hydrogels; mixing; molecular biophysics; photochemistry; amino moieties; amino terminated biocompatible polymers; amino-terminated tetraarm poly(ethylene glycol); biocompatible polymers; gelatin; microscale cell manipulation; mixing; one-step reaction; photocleavable crosslinker; photodegradable hydrogel; Chemicals; Degradation; Plastics; Radiation effects; Spatiotemporal phenomena; Three-dimensional displays;

fLanguage

English

Publisher

ieee

Conference_Titel

Micro-NanoMechatronics and Human Science (MHS), 2014 International Symposium on

Conference_Location

Nagoya

Print_ISBN

978-1-4799-6678-3

Type

conf

DOI

10.1109/MHS.2014.7006089

Filename

7006089