Title :
Experimental study on dielectric properties of yeast cells in micro channel by impedance spectroscopy
Author :
Jiafeng Yao ; Kodera, Tatsuya ; Sapkota, Archana ; Obara, Hiromichi ; Takei, Manabu
Author_Institution :
Grad. Sch. of Mech. Eng., Chiba Univ., Chiba, Japan
Abstract :
Impedance spectroscopy has been proved to be a useful technique for analyzing heterogeneous systems, especially biological cell suspensions and tissues because of its capacity of non-invasive measurement. In the present paper, experiments were conducted to study the dielectric properties of yeast cells by Impedance Spectroscopy. The capacitance of the suspension of yeast cells was measured and the relative permittivity and the dielectric loss were calculated. As the concentration of yeast cells increased, the relative permittivity and the dielectric loss were also increased. In addition, the relative permittivity and the dielectric loss of living cells were higher than that of the dead ones. Finally, we concluded that it is possible to sense the status and the concentration of cell suspension by impedance spectroscopy.
Keywords :
bioMEMS; bioelectric phenomena; capacitance measurement; cellular biophysics; dielectric losses; electrochemical impedance spectroscopy; microchannel flow; microorganisms; permittivity; suspensions; biological cell suspensions; biological tissues; dielectric loss; dielectric properties; heterogeneous systems; impedance spectroscopy; living cells; microchannel; noninvasive measurement; relative permittivity; suspension capacitance; yeast cell concentration; Dielectrics; Electrodes; Impedance; Microchannels; Permittivity; Spectroscopy; Suspensions; Dielectric; Impedance Spectroscopy; Multi-layered Microchannel; Yeast;
Conference_Titel :
Micro-NanoMechatronics and Human Science (MHS), 2014 International Symposium on
Conference_Location :
Nagoya
Print_ISBN :
978-1-4799-6678-3
DOI :
10.1109/MHS.2014.7006168