Visualization of tissue collagen with femtosecond laser: application to skin diagnosis and cell culture

Author

Araki, Takeshi

Author_Institution

Dept. of Mech. Sci. & Eng., Osaka Univ., Toyonaka, Japan

fYear

2014

fDate

4-6 Nov. 2014

Firstpage

1

Lastpage

2

Abstract

Femtosecond laser induced second harmonic generation (SHG) microscopy provides non-invasive and non-staining observation of collagen structure. In this article, application of SHG microscopy for skin diagnosis and for engineered cell culture are demonstrated.

Keywords

biomedical engineering; biomedical equipment; biomedical optical imaging; cellular biophysics; high-speed optical techniques; laser applications in medicine; molecular biophysics; molecular configurations; optical harmonic generation; optical microscopy; proteins; skin; SHG microscopy application; cell culture application; cell culture engineering; femtosecond laser; noninvasive collagen structure observation; nonstaining collagen structure observation; second harmonic generation microscopy; skin diagnosis application; tissue collagen visualization; Laser mode locking; Measurement by laser beam; Microscopy; Optical attenuators; Optical fiber polarization; Optical microscopy; Skin; SHG light; collagen; engineered cell; in situ visualization; laser microscope;

fLanguage

English

Publisher

ieee

Conference_Titel

CPMT Symposium Japan (ICSJ), 2014 IEEE

Conference_Location

Kyoto

Print_ISBN

978-1-4799-6194-8

Type

conf

DOI

10.1109/ICSJ.2014.7009594

Filename

7009594