Title :
Evolutionary inference of biochemical reaction networks accelerated on graphics processing units
Author :
Nobile, M.S. ; Mauri, G.
Author_Institution :
Dipt. di Inf., Sist. e Comun., Univ. degli Studi di Milano-Bicocca, Milan, Italy
Abstract :
The reverse engineering (RE) of biochemical reaction networks is a fundamental and very complex task in Systems Biology. My PhD thesis is focused on the definition of an automatic RE methodology based on the fusion of Genetic Programming and Particle Swarm Optimization. The methodology I propose relies on the execution of a massive number of simulations, whose computational costs are relevant. To the aim of reducing the overall running time, I am implementing the methodology on a parallel architecture, namely, Nvidia´s CUDA.
Keywords :
biochemistry; biology computing; genetic algorithms; graphics processing units; particle swarm optimisation; CUDA; Nvidia; automatic RE methodology; biochemical reaction networks; evolutionary inference; genetic programming; graphics processing units; parallel architecture; particle swarm optimization; reverse engineering; systems biology; Biological system modeling; Chemicals; Computational modeling; Genetic programming; Graphics processing units; Kinetic theory; Mathematical model; GPGPU Computing; Genetic Programming; Particle Swarm Optimization; Reverse Engineering; Systems Biology;
Conference_Titel :
High Performance Computing and Simulation (HPCS), 2013 International Conference on
Conference_Location :
Helsinki
Print_ISBN :
978-1-4799-0836-3
DOI :
10.1109/HPCSim.2013.6641490