Title :
Formation of tin(IV) protoporphyrin reconstituted myoglobin and its stability toward light
Author :
Lewis, Ben ; Prasad, Shiva ; Thordarson, Pall
Author_Institution :
Sch. of Chem., Univ. of New South Wales, Sydney, NSW, Australia
Abstract :
We report the synthesis of a tin(IV) protoporphyrin reconstituted myoglobin from apomyoglobin and tin(IV) protoporphyrin and examine its stability toward light. Light stability studies show that the reconstituted myoglobin does not maintain structural integrity upon exposure to light and suggests that tin(IV) protoporphyrin leads to the degradation of the protein through reactions that are photocatalytic in manner.
Keywords :
biochemistry; biological effects of optical radiation; biomolecular effects of radiation; catalysis; photochemistry; proteins; apomyoglobin; light stability; photocatalysis; protein; structural integrity; tin(IV) protoporphyrin reconstituted myoglobin; Absorption; Degradation; Nanostructures; Nuclear magnetic resonance; Proteins; Self-assembly; Solvents; bio-hybrid; myoglobin; photocatalyst; porphyrin; reconstitution;
Conference_Titel :
Nanoscience and Nanotechnology (ICONN), 2010 International Conference on
Conference_Location :
Sydney, NSW
Print_ISBN :
978-1-4244-5261-3
Electronic_ISBN :
978-1-4244-5262-0
DOI :
10.1109/ICONN.2010.6045231