Title :
Can voronoi diagram model cell geometries in early sea-urchin embryogenesis?
Author :
Luengo-Oroz, M.A. ; Duloquin, L. ; Castro, C. ; Savy, T. ; Faure, E. ; Lombardot, B. ; Bourgine, P. ; Peyrieras, N. ; Santos, A.
Author_Institution :
Biomed. Image Technol. Lab., Univ. Politec. de Madrid, Madrid
Abstract :
We test the hypothesis that cell membranes in early sea- urchin embryos can be modeled as a Voronoi diagram from nuclei centers. In order to obtain a model of the cell geometry against which to test our Voronoi model hypothesis, we developed a viscous watershed framework that allows segmenting 3D images of living sea-urchin embryos obtained by biphoton laser scanning microscopy. Measurements of the differences between segmented cells and the Voronoi model, show an interesting high correlation that can serve for developing more accurate methods of segmentation and modelling cell geometries.
Keywords :
biomembranes; cellular biophysics; computational geometry; image segmentation; optical microscopy; 3D image segmentation; Voronoi diagram; biphoton laser scanning microscopy; cell geometries; cell membranes; sea urchin embryogenesis; Biomembranes; Cells (biology); Embryo; Geometrical optics; Geometry; Image segmentation; Laser modes; Microscopy; Solid modeling; Testing; Microscopy; biological cells; image segmentation; morphological operations;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2008. ISBI 2008. 5th IEEE International Symposium on
Conference_Location :
Paris
Print_ISBN :
978-1-4244-2002-5
Electronic_ISBN :
978-1-4244-2003-2
DOI :
10.1109/ISBI.2008.4541043