Title :
Contactless characterization of yeast cell cultivation at 7 GHz and 240 GHz
Author :
Wessel, Jan ; Schmalz, K. ; Cahill, B.P. ; Gastrock, G. ; Meliani, Chafik
Author_Institution :
IHP, Frankfurt (Oder), Germany
Abstract :
Experimental results of contactless and label-free characterization techniques of cell cultivation are presented. The two demonstrated approaches are compared at two frequencies, 7 GHz and 240 GHz in terms of sensitivity and applicability. At 7 GHz, measurements have been performed using a rat-race based characterizing system. Furthermore, the sensitivity of spectroscopy measurements at 240 GHz has been compared for two extracted parameters: phase and amplitude. The conducted experiments demonstrate that by selecting the proper characterization parameter, the presented techniques are suitable for cell cultivation monitoring in a pipe based microfluidic system with PTFE tubes. Especially, the use of higher frequencies enables a higher compactness.
Keywords :
microfluidics; millimetre wave measurement; phase measurement; pipes; sensitivity; spectroscopy; PTFE tubes; amplitude parameters; cell cultivation monitoring; characterization parameter; contactless characterization; frequency 240 GHz; label-free characterization techniques; phase parameters; pipe-based microfluidic system; rat-race based characterizing system; spectroscopy measurement sensitivity; yeast cell cultivation; Biosensors; Microfluidics; Microwave measurement; Microwave theory and techniques; Permittivity; Photoconductivity; Sugar; biosensor; label-free; microfluidic; permittivity; sub-THz microwave;
Conference_Titel :
Power Amplifiers for Wireless and Radio Applications (PAWR), 2013 IEEE Topical Conference on
Conference_Location :
Santa Clara, CA
Print_ISBN :
978-1-4673-2915-6
Electronic_ISBN :
978-1-4673-2931-6
DOI :
10.1109/PAWR.2013.6490194