DocumentCode :
1821427
Title :
Modeling and characterizing collagen fiber bundles
Author :
Elbischger, P.J. ; Cacho, F. ; Bischof, H. ; Holzapfel, G.A.
Author_Institution :
Medical Information Technol., University of Applied Sci.
fYear :
2006
fDate :
6-9 April 2006
Firstpage :
1280
Lastpage :
1283
Abstract :
Collagen fibers are prominent constituents of many soft tissues. The fibers are able to carry load along their fiber axis, and, therefore, their structural arrangement renders the mechanical behavior of biological tissue anisotropic. In some tissues, e.g., blood vessels, tendons and ligaments, the fibers form fiber bundles. Structure-based biomechanical models of soft tissues strongly rely on a clear understanding of the underlying collagen fiber bundle structure and require precise quantitative structural information. The paper presents a novel fiber bundle model that satisfactorily explains the observed bundle structure and reveals meaningful parameters for bundle characterization. The model is capable of describing a wide variety of natural bundle structures. It is shown that the identified bundle parameters can be extracted from real histological images using computer vision algorithms. The generative nature of the model allows the creation of artificial fiber bundle images with characteristics very similar to real images
Keywords :
biomechanics; biomedical optical imaging; blood vessels; computer vision; medical image processing; molecular biophysics; physiological models; proteins; blood vessels; collagen fiber bundle structure; computer vision algorithms; histological images; ligaments; parameter extraction; soft tissues; structure-based biomechanical models; tendons; Anisotropic magnetoresistance; Biological system modeling; Biological tissues; Biomedical imaging; Blood vessels; Character generation; Computer vision; Data mining; Ligaments; Tendons;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Biomedical Imaging: Nano to Macro, 2006. 3rd IEEE International Symposium on
Conference_Location :
Arlington, VA
Print_ISBN :
0-7803-9576-X
Type :
conf
DOI :
10.1109/ISBI.2006.1625159
Filename :
1625159
Link To Document :
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