Title :
The effects of different capillary structures on BOLD model in functional MR imaging
Author :
Tsai, Chi-Ming ; Chen, Jyh-Horng
Author_Institution :
Dept. of Electr. Eng., Nat. Taiwan Univ., Taipei, Taiwan
Abstract :
Simulation results using the Monte Carlo method to evaluate the MRI signal loss due to intravascular susceptibility difference under different capillary structures are presented in this report. These data reveal a simplified periodic structure which is a good approximation to the complicated random structure when the diffusion constant of water is larger than 10-9 m2/sec for gradient echo and 2×10-9 m2/sec for spin echo at a typical cerebral blood volume fraction (f=5%)
Keywords :
Monte Carlo methods; biomedical NMR; magnetic susceptibility; physiological models; BOLD model; MRI signal loss; Monte Carlo method; capillary structures effects; functional MR imaging; intravascular susceptibility difference; magnetic resonance imaging; medical diagnostic imaging; water diffusion constant; Blood; Gaussian distribution; Magnetic fields; Magnetic resonance imaging; Magnetization; Monte Carlo methods; Nonuniform electric fields; Paramagnetic materials; Periodic structures; Random number generation;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.411897
