A Computational Model of Rat Cerebral Blood Flow using Non-Uniform Rational B-splines

Author

Pushkin, S.V. ; Podoprigora, G.I. ; Comas, L. ; Boulahdour, H. ; Cardot, J.-C. ; Baud, M. ; Nartsissov, Y.R. ; Blagosklonov, O.

Author_Institution

Inst. of Cytochemist. & Mol. Pharmacology, Moscow

fYear

2007

fDate

22-26 Aug. 2007

Firstpage

1098

Lastpage

1100

Abstract

Non-Uniform Rational B-splines (NURBS) surfaces can be used for a computer simulation of shapes. Some anatomical models of human or animal structures have been recently developed on that basis. We used positron-emission tomography (PET) and computed tomography (CT) data for NURBS modeling of anatomical structures and isotope uptake in the rat brain. Our simplified model of the rat cerebral blood flow is the first step in a larger project aiming a simulation of PET scans in small animals followed by its validation in vivo.

Keywords

biology computing; brain; computerised tomography; haemodynamics; positron emission tomography; splines (mathematics); CT data; NURBS anatomical structure modeling; PET data; computed tomography; nonuniform rational B-splines; positron emission tomography; rat brain anatomical structures; rat brain isotope uptake; rat cerebral blood flow; Blood flow; Brain modeling; Computational modeling; Computed tomography; Computer simulation; Positron emission tomography; Shape; Spline; Surface reconstruction; Surface topography; Algorithms; Animals; Brain; Cerebrovascular Circulation; Computer Simulation; Fluorodeoxyglucose F18; Image Interpretation, Computer-Assisted; Models, Anatomic; Models, Cardiovascular; Models, Neurological; Numerical Analysis, Computer-Assisted; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Tomography, X-Ray Computed;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE

Conference_Location

Lyon

ISSN

1557-170X

Print_ISBN

978-1-4244-0787-3

Type

conf

DOI

10.1109/IEMBS.2007.4352487

Filename

4352487