Title :
A Computational Model of Rat Cerebral Blood Flow using Non-Uniform Rational B-splines
Author :
Pushkin, S.V. ; Podoprigora, G.I. ; Comas, L. ; Boulahdour, H. ; Cardot, J.-C. ; Baud, M. ; Nartsissov, Y.R. ; Blagosklonov, O.
Author_Institution :
Inst. of Cytochemist. & Mol. Pharmacology, Moscow
Abstract :
Non-Uniform Rational B-splines (NURBS) surfaces can be used for a computer simulation of shapes. Some anatomical models of human or animal structures have been recently developed on that basis. We used positron-emission tomography (PET) and computed tomography (CT) data for NURBS modeling of anatomical structures and isotope uptake in the rat brain. Our simplified model of the rat cerebral blood flow is the first step in a larger project aiming a simulation of PET scans in small animals followed by its validation in vivo.
Keywords :
biology computing; brain; computerised tomography; haemodynamics; positron emission tomography; splines (mathematics); CT data; NURBS anatomical structure modeling; PET data; computed tomography; nonuniform rational B-splines; positron emission tomography; rat brain anatomical structures; rat brain isotope uptake; rat cerebral blood flow; Blood flow; Brain modeling; Computational modeling; Computed tomography; Computer simulation; Positron emission tomography; Shape; Spline; Surface reconstruction; Surface topography; Algorithms; Animals; Brain; Cerebrovascular Circulation; Computer Simulation; Fluorodeoxyglucose F18; Image Interpretation, Computer-Assisted; Models, Anatomic; Models, Cardiovascular; Models, Neurological; Numerical Analysis, Computer-Assisted; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Tomography, X-Ray Computed;
Conference_Titel :
Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE
Conference_Location :
Lyon
Print_ISBN :
978-1-4244-0787-3
DOI :
10.1109/IEMBS.2007.4352487
