Title :
Viologen-mediated transmembrane oxidation-reduction
Author :
Patterson, Brian C. ; Kuhn, Eberhardt ; Hurst, James K.
Author_Institution :
Dept. of Chem. & Biol. Sci., Oregon Graduate Center, Beaverton, OR, USA
Abstract :
A mechanism for oxidation-reduction reactions occurring across bilayer membranes is identified from kinetic studies on viologens bound to vesicles and from stoichiometric analyses of viologen redistribution accompanying the reaction. The viologens, as the only lipophilic ions in the system, diffuse in response to membrane electrical potential, and consequently track the movement of the electron
Keywords :
bioelectric potentials; biomembranes; cellular biophysics; bilayer membranes; electron; kinetic studies; lipophilic ions; membrane electrical potential; oxidation-reduction reactions; stoichiometric analyses; vesicles; viologen mediated transmembrane oxidation reduction; viologen redistribution; Assembly; Biochemical analysis; Biology; Biomembranes; Chemical analysis; Electric potential; Electrons; Kinetic theory; Tracking; Tunneling;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.96218
