Title :
MicroPET performance in the presence of the third gamma
Author :
Converse, Alexander K. ; Nye, Jonathon A. ; Barnhart, Todd E. ; Dick, David W. ; Avila-Rodriguez, Miguel A. ; Sundaresan, Ramya ; Dallas, Corinne B. ; Nickles, Robert J. ; Kalin, Ned H. ; Roberts, Andrew D.
Author_Institution :
Keck Laboratory for Functional Brain Imaging, Wisconsin Univ., Madison, WI, USA
Abstract :
Isotopes in routine use for positron emission tomography (PET) produce only a single pair of 511 keV annihilation photons. "Dirty" positron emitters, e.g. 124I, that emit additional gammas are increasingly of interest. Performance of the Concorde microPET P4 small animal scanner was experimentally studied. Three phantoms were used to compare the pure positron emitter 18F to 124I and the convenient proxies 70As and 72As. While the third gamma had only a small impact on images of a contrast/detail phantom, resolution of hot sources on cold background was noticably reduced in a "Derenzo" phantom. A "NEMA" phantom exhibited a 15% background due to the third gamma.
Keywords :
arsenic; fluorine; gamma-ray detection; image resolution; iodine; medical image processing; phantoms; positron emission tomography; radioisotopes; 124I; 18F; 70As; 72As; Concorde microPET P4 small animal scanner; Derenzo phantom; NEMA phantom; contrast/detail phantom; dirty positron emitters; hot source resolution; isotopes; positron emission tomography; third gamma; Animals; Chemistry; Gamma ray detection; Gamma ray detectors; Germanium; Imaging phantoms; Isotopes; Myocardium; Positron emission tomography; Single photon emission computed tomography;
Conference_Titel :
Nuclear Science Symposium Conference Record, 2003 IEEE
Print_ISBN :
0-7803-8257-9
DOI :
10.1109/NSSMIC.2003.1352227
