Title :
Self-assembly as a mechanism of molecular computing
Author_Institution :
Dept. of Comput. Sci., Wayne State Univ., Detroit, MI, USA
Abstract :
A physical mode of computing is proposed in which symbolic pattern recognition problems are converted to free energy minimization problems. Signals impinging on the external surface of a cell (an artificial device or possibly a biological cell) release distinct macromolecules that self-assemble into higher level shapes. Readout enzymes link the physiochemical properties (e.g. shape features) of these aggregates to effector enzymes that control the output of the cell
Keywords :
biology computing; molecular biophysics; artificial device; biological cell; cell output control; free energy minimization problems; macromolecular self-assembly; molecular computing mechanism; physical mode of computing; physiochemical properties; readout enzymes; shape features; symbolic pattern recognition problems; Aggregates; Biochemistry; Biological cells; Biology computing; Cells (biology); Molecular computing; Pattern recognition; Physics computing; Self-assembly; Shape control;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.96236
