DocumentCode
1829479
Title
Structural Character of Protein Complex a-syn12 Peptide and Synphilin-1 Studied Using Molecular Dynamics Simulation
Author
Zhao, Liling
Author_Institution
Key Lab. of Biophys. in Univs. of Shandong, Dezhou Univ., Dezhou, China
fYear
2010
fDate
15-16 May 2010
Firstpage
23
Lastpage
25
Abstract
Molecular dynamics simulations method was used to study the dynamics and structural character of α-syn12 peptide complex with synphilin-1 protein in aqueous solution at low pH by using GROMOS 43A1 force field. The α-syn12 peptide aggregates faster at low pH than at neutral pH.
Keywords
biological techniques; molecular biophysics; molecular dynamics method; pH; proteins; GROMOS 43A1 force field; aqueous solution; molecular dynamics simulation; neutral pH; protein complex α-syn12 peptide; synphilin-1 protein; Biological system modeling; Computational modeling; Dynamics; Force; Parkinson´s disease; Peptides; Proteins; a-syn12; force field; molecular dynamics simulation; protein complex;
fLanguage
English
Publisher
ieee
Conference_Titel
Modeling, Simulation and Visualization Methods (WMSVM), 2010 Second International Conference on
Conference_Location
Sanya
Print_ISBN
978-1-4244-7077-8
Electronic_ISBN
978-1-4244-7078-5
Type
conf
DOI
10.1109/WMSVM.2010.14
Filename
5558345
Link To Document